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Multivariate data analysis methods

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Labial salivary gland (LSG) biopsy is used in the classification of primary Sjgren’s syndrome (PSS) and in patient stratification in clinical trials. It may also function as a biomarker. The acquisition of tissue and histological interpretation is variable and needs to be standardised for use in clinical trials.

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Gondii infection may enhance the understanding of the molecular mechanisms that define the pathophysiology of T. Gondii using LC MS/MS based metabolomics. Multivariate data analysis methods, principal components analysis (PCA) and partial least squares discriminant analysis (PLS DA), were used to identify metabolites that are influenced by T.

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