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He said: ”I could have easily been like ‘Hey

However, carnosine quantification by 1H MRS has some potential limitations that warrant a thorough experimental examination of its validity. The present investigation examined the reliability, accuracy and sensitivity for the determination of muscle carnosine in humans using in vitro and in vivo experiments and comparing it to reference method for carnosine quantification (high performance liquid chromatography HPLC). We used in vitro 1H MRS to verify signal linearity and possible noise sources.

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